STRUCTURAL MODELLING OF THE LUMENAL DOMAIN OF HUMAN GPAA1, THE METALLO-PEPTIDE SYNTHETASE SUBUNIT OF THE TRANSAMIDASE COMPLEX, REVEALS ZINC-BINDING MODE AND TWO FLAPS SURROUNDING THE ACTIVE SITE

Abstract Background The transamidase complex is a molecular machine in the endoplasmic reticulum of eukaryotes that attaches a glycosylphosphatidylinositol (GPI) lipid anchor to substrate proteins after cleaving a C-terminal propeptide with a defined sequence signal.Its five subunits are very hydrophobic; Fridge Light Switch thus, solubility, heter

Zhibing Tang,1,2,* Lin Zhao,1,3,* Zaixing Yang,3 Zhaohui Liu,4 Jia Gu,3 Bing Bai,3 Jinlian Liu,2 Jiaying Xu,3 Huilin Yang1 1Department of Orthopedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, China; 2Department of Orthopaedic Surgery, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, S

Anchote (Coccinia abyssinica) is an indigenous tuber crop of the Ethiopian Highlands.It is popular in the western Oromia Region of the country.Apart from food, the crop is also used in traditional medicine.Anchote tubers possess two variations in its tissue colour, red and white.In this study, a small market survey and a nutritional comparison of r